Giuseppe Valacchi Selected Research

rottlerin

11/2019	Multiple mechanisms of Rottlerin toxicity in A375 melanoma cells.
1/2015	Antiproliferative Effect of Rottlerin on Sk-Mel-28 Melanoma Cells.
1/2012	Alternative Pathways of Cancer Cell Death by Rottlerin: Apoptosis versus Autophagy.
6/2011	Rottlerin exhibits antiangiogenic effects in vitro.
6/2010	Rottlerin: bases for a possible usage in psoriasis.
6/2009	Rottlerin: a multifaced regulator of keratinocyte cell cycle.

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Giuseppe Valacchi Research Topics

Disease

32	Inflammation (Inflammations) 04/2022 - 10/2002
28	Rett Syndrome (Rett's Disorder) 01/2022 - 08/2009
12	Neurodevelopmental Disorders 06/2021 - 08/2009
10	Melanoma (Melanoma, Malignant) 06/2022 - 01/2015
9	Wounds and Injuries (Trauma) 05/2022 - 01/2006
9	Neoplasms (Cancer) 03/2022 - 11/2003
8	Psoriasis (Pustulosis Palmaris et Plantaris) 04/2022 - 06/2010
8	Alzheimer Disease (Alzheimer's Disease) 11/2021 - 06/2016
5	Neuroblastoma 01/2021 - 11/2010
5	Skin Diseases (Skin Disease) 01/2020 - 06/2010
4	Acne Vulgaris 04/2022 - 01/2003
4	Atopic Dermatitis (Atopic Eczema) 04/2022 - 07/2019
4	Obesity 02/2018 - 01/2012
4	Autistic Disorder (Autism) 01/2016 - 01/2013
4	Disease Progression 01/2014 - 07/2011
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2020 - 05/2010
3	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2019 - 12/2016
3	Cognitive Dysfunction 01/2018 - 06/2016
3	Autism Spectrum Disorder 01/2017 - 01/2013
3	Acute-Phase Reaction 01/2013 - 10/2004
3	Lung Diseases (Lung Disease) 07/2012 - 09/2002
2	Vitiligo 04/2022 - 09/2010
2	Infections 05/2021 - 01/2020
2	Premature Aging 01/2021 - 07/2019
2	Atherosclerosis 01/2021 - 12/2016
2	Mitochondrial Diseases (Mitochondrial Disease) 12/2020 - 10/2015
2	Cardiovascular Diseases (Cardiovascular Disease) 02/2018 - 12/2014
2	Dementia (Dementias) 01/2018 - 06/2016
2	Mixed Dementias 01/2018 - 12/2016
2	Genetic Predisposition to Disease (Genetic Predisposition) 07/2012 - 05/2010
2	Breast Neoplasms (Breast Cancer) 01/2012 - 06/2011
1	Carcinogenesis 01/2022
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2022
1	Body Weight (Weight, Body) 12/2021
1	Sarcopenia 05/2021
1	Measles 01/2021
1	Mumps 01/2021
1	Temporal Lobe Epilepsy 01/2021
1	Epilepsy (Aura) 01/2021
1	Eczema 01/2021

Drug/Important Bio-Agent (IBA)

18	Methyl-CpG-Binding Protein 2IBA 06/2021 - 08/2009
17	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2006
11	Biomarkers (Surrogate Marker)IBA 11/2021 - 12/2011
11	AntioxidantsIBA 01/2021 - 04/2008
9	LipidsIBA 02/2018 - 01/2010
8	CytokinesIBA 01/2016 - 10/2002
7	Environmental Pollutants (Pollutants, Environmental)IBA 01/2022 - 07/2012
7	Pharmaceutical PreparationsIBA 01/2020 - 01/2003
6	SmokeIBA 04/2022 - 05/2010
6	OzoneIBA 01/2022 - 07/2012
6	rottlerinIBA 11/2019 - 06/2009
5	InflammasomesIBA 04/2022 - 01/2020
5	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 11/2014 - 05/2011
4	Biological ProductsIBA 01/2021 - 11/2010
4	Lipoproteins (Lipoprotein)IBA 01/2021 - 01/2017
4	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2020 - 02/2013
4	EnzymesIBA 01/2020 - 11/2010
4	Aryldialkylphosphatase (Paraoxonase)IBA 06/2019 - 12/2016
4	Scavenger Receptors (Scavenger Receptor)IBA 01/2018 - 07/2013
3	MicroRNAs (MicroRNA)IBA 06/2022 - 01/2017
3	Particulate MatterIBA 01/2022 - 01/2020
3	Air Pollutants (Pollutants, Air)IBA 01/2021 - 07/2012
3	Amyloid (Amyloid Fibrils)IBA 01/2020 - 06/2016
3	arylesteraseIBA 02/2018 - 12/2016
3	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 10/2017 - 09/2010
3	Messenger RNA (mRNA)IBA 04/2015 - 09/2010
3	high density lipoprotein receptorsIBA 03/2015 - 07/2013
2	ChromatinIBA 06/2021 - 01/2013
2	ProteomeIBA 01/2021 - 01/2013
2	NF-kappa B (NF-kB)IBA 01/2021 - 01/2015
2	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 06/2009
2	Bromodeoxyuridine (BrdU)IBA 01/2020 - 09/2015
2	Transcription Factors (Transcription Factor)IBA 01/2020 - 10/2018
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020 - 10/2015
2	Cytostatic AgentsIBA 11/2019 - 01/2015
2	Phospholipases A2 (Phospholipase A2)IBA 01/2018 - 01/2017
2	C-Reactive ProteinIBA 01/2018 - 01/2018
2	HDL LipoproteinsIBA 12/2016 - 02/2014
2	ChemokinesIBA 01/2016 - 09/2010
2	Carotenoids (Carotene)IBA 03/2015 - 11/2003
2	CholesterolIBA 02/2014 - 01/2014
2	IronIBA 02/2013 - 11/2010
2	Vascular Endothelial Growth FactorsIBA 01/2013 - 01/2011
2	adrenic acid (7,10,13,16-docosatetraenoic acid)IBA 01/2013 - 12/2011
2	Protein Isoforms (Isoforms)IBA 01/2013 - 09/2010
2	LipopolysaccharidesIBA 03/2007 - 10/2004
1	QuercetinIBA 05/2022
1	Volatile Organic CompoundsIBA 03/2022
1	InterleukinsIBA 01/2022
1	Caspase 1 (ICE Protease)IBA 01/2022
1	Silicon Dioxide (Silica)FDA LinkGeneric 12/2021
1	NitrogenIBA 11/2021
1	OxidesIBA 11/2021
1	HydrocarbonsIBA 11/2021
1	Sulfur DioxideIBA 11/2021
1	Cholecalciferol (Vitamin D3)FDA Link 05/2021
1	involucrinIBA 01/2021
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021

Therapy/Procedure

5	Therapeutics 01/2020 - 05/2011
2	Radiotherapy 01/2019 - 01/2012